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TLR3 Antibody
Rabbit Polyclonal
600-401-H26
100 µg
Liquid (sterile filtered)
WB, ELISA, IHC, IF
Human, Mouse
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-TLR3 (RABBIT) Antibody - 600-401-H26
Toll-like receptor 3, CD283
Rabbit
Polyclonal
IgG
Target Details
TLR3 - View All TLR3 Products
Human, Mouse
Conjugated Peptide
TLR3 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids near the c-terminus of human TLR3.
Anti-TLR-3 Antibody was affinity purified. A BLAST analysis was used to suggest cross-reactivity with TLR3 with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with TRL3 from other sources has not been determined. This polyclonal antibody will not react with TRL1.
Application Details
ELISA, IF, IHC, WB
Anti-TLR3 Antibody is tested for use in E, WB, IF, IHC and ICC. Expect a band approximately ~103.8 kDa on specific lysates. Western Blot in human and mouse samples; Immunohistochemistry in human and mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in human and mouse samples. Specific conditions for reactivity should be optimized by the end user.
Formulation
1.0 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.02% (w/v) Sodium Azide
None
Shipping & Handling
Wet Ice
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Expiration date is one (1) year from date of receipt.
TLR3 antibody detects the human TLR3. Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection. Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus. Anti-TRL3 antibodies are ideal for investigators involved in kinase and phosphatase, transcription factors and infectious disease research.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
