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SOD1 Antibody
Rabbit Polyclonal
600-401-F19
100 µg
Liquid (sterile filtered)
WB, IHC, IF, IP
Human, Mouse, Rat, Bovine
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-SOD1 (RABBIT) Antibody - 600-401-F19
Superoxide dismutase1, Superoxide dismutase Cu-Zn, ALS1, IPOA, SOD1, SOD2, SODC, hSod1
Rabbit
Polyclonal
IgG
Target Details
Sod1 - View All Sod1 Products
Human, Mouse, Rat, Bovine
Conjugated Peptide
SOD1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to rat SOD1.
Anti-SOD1 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with SOD1 from Human, Rat, Mouse, and Bovine based on 100% homology with the immunizing sequence. Cross-reactivity with SOD1 from other sources has not been determined.
P07632 - UniProtKB
NP_058746.1 - NCBI Protein
Application Details
IF, IHC, IP, WB
Anti-SOD1 Antibody is tested for use in WB, IP, IF, and IHC. Expect a band approximately ~23kDa (human) and 19kDa (other species) proteins corresponding to the molecular mass of superoxide dismutase (SOD1) on SDS PAGE immunoblots. Specific conditions for reactivity should be optimized by the end user.
Formulation
1.0 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.09% (w/v) Sodium Azide
50% (v/v) Glycerol
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.