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SMYD2 protein-GST fusion
009-001-T43S
009-001-T43
20 µg
50 µg
Liquid (sterile filtered)
Liquid (sterile filtered)
Human
Sf9 cells
This product is discontinued
Product Details
SMYD2 recombinant protein-GST fusion protein - 009-001-T43
KMT3C, HSKM-B, ZMYND14, SET and MYND domain containing 2
Human
Sf9 cells
Recombinant Protein
Target Details
SMYD2
Recombinant full-length human SMYD2 was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >85% by densitometry.
?term=BC049367 - Gene ID
Application Details
SMYD2 Protein is stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. SMYD2 Protein is suitable for use in Western Blot. Expect a band approximately ~70kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
Formulation
0.1 µg/µL
See application note.
Shipping & Handling
Dry Ice
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Expiration date is one (1) year from date of receipt.
SMYD2 (also known as SET and MYND domain-containing protein 2) is a member of the SMYD family of protein methyltransferases. SMYD2 is also known as lysine methyltransferase protein 3C (KMT3C). SMYD2 functions to repress transcription by interacting with the Sin3A histone deacetylase complex and performs methylation of Lys36 in histone H3 (1). The exogenous expression of SMYD2 in mouse fibroblasts decreases cell growth. SMYD2 also function as a putative oncogene by methylating p53 and repressing its tumor suppressive function (2). SMYD2 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.