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IL-35 EBI3 Mouse Recombinant Protein
1 References
010-001-B66
10 µg
Lyophilized
SDS-PAGE, Other
Mouse
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
EBI-3 Mouse Recombinant Protein - 010-001-B66
Interleukin-27 subunit beta precursor [Mus musculus], mouse EBI-3 cytokine, EBI3, EBI-3, IL35, IL-35
Mouse
Recombinant Protein
Target Details
Ebi3 - View All Ebi3 Products
Recombinant protein corresponding to amino acids 2 to 207 of mature mouse EBI-3. Purity is greater than 90% as determined by reducing and non-reducing SDS-PAGE and by analytical HPLC, each against a known standard.
O35228 - UniProtKB
Application Details
SDS-PAGE
Other
- View References
EBI-3 protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-EBI-3 in immunological assays.
Formulation
0.1 mg/mL by UV absorbance at 280 nm
0.1% Trifluoroacetic acid
None
None
100 µL
0.02M HCl
Shipping & Handling
Ambient
Store vial at -20° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL) . For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
Expiration date is six (6) months from date of receipt.
Epstein-Barr Virus Induced Gene-3 (EBI-3), is a secreted glycoprotein belonging to the hematopoietin receptor family and related to the p40 subunit of IL-12. It was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI-3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity. Recombinant Mouse EBI is a non-glycosylated polypeptide chain consisting of 207 amino acids with a molecular weight of 22,900 Da.
Nikolic I et al. (2024). Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis. EMBO Rep.
Applications
Immunization
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
