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TLR7 Antibody
Rabbit Polyclonal
1 References
200-401-A64
100 µg
Liquid (sterile filtered)
WB, ELISA, IHC, IF
Human
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-TLR7 (RABBIT) Antibody - 200-401-A64
PRO285 antibody, Toll like receptor 7 antibody, UNQ248 antibody
Rabbit
Polyclonal
IgG
Target Details
Tlr7 - View All Tlr7 Products
Human
Conjugated Peptide
TLR7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to an internal region of mouse TLR7.
Anti-TLR7 Antibody was purified from monospecific antiserum. This product is affinity chromatography purified via peptide column. A BLAST analysis was used to suggest cross-reactivity with TLR7 with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with TLR7 from other sources has not been determined.
Application Details
ELISA, IHC, WB
IF
- View References
TLR7 Antibody has been tested for use in ELISA, immunocytochemistry, and western blotting. Expect a band at ~121 kDa in size corresponding to TLR7 by western blotting in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
Formulation
1.0 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.02% (w/v) Sodium Azide
None
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFN secretion, suggesting the importance of TLR7 in virus recognition. Anti-TLR7 antibody is ideal for investigators involved in kinases, phosphatase, cytokines, growth factors and transcription factor research.
Sauter MM et al. (2018). Toll-like receptors 4, 5, 6 and 7 are constitutively expressed in non-human primate retinal neurons. J Neuroimmunol.
Applications
IF, Confocal Microscopy; WB, IB, PCA
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.