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NMDA R2C phospho S1096 Antibody
Rabbit Polyclonal
600-401-D95
100 µL
Liquid
WB
Mouse, Rat
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-NMDA R2C pS1096 (RABBIT) Antibody - 600-401-D95
Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C
Rabbit
Polyclonal
IgG
Target Details
Grin2c - View All Grin2c Products
Mouse, Rat
Phosphorylation
Conjugated Peptide
Anti-NMDA R2C pS1096 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1096.
Anti-NMDA R2C pS1096 antibody is directed against phosphorylated NMDA 2C receptor protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. The antibody is specific for NMDA 2C receptor phosphorylated at S1096. Reactivity is expected from the following species based on 100% sequence homology: bovine, canine, human and non-human primates.
Q00961 - UniProtKB
Application Details
WB
Anti-NMDA R2C pS1096 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 140 kDa in size corresponding to the NR2C subunit of the NMDA receptor phosphorylated at Ser1096 in the appropriate cell lysate or extract.
Formulation
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
NMDA R2C pS1096 antibody detects NMDA 2C receptor protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR2C subunit of the receptor is thought to influence the NMDAR conductance level. Phosphorylation of Ser1096 by PKB on NR2C has been recently demonstrated to regulate NMDA receptor binding to 14-3-3. Anti-NMDA R2C pS1096 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
