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LRRK2/Dardarin Antibody Phycoerythrin
Mouse Monoclonal S138-6 IgG1
200-308-W60
100 µg
Liquid (sterile filtered)
WB, IHC
Human, Mouse, Rat
Mouse
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-LRRK2/Dardarin (MOUSE) Monoclonal Antibody Phycoerythrin Conjugated - 200-308-W60
Leucine-rich repeat kinase 2, RIP7, PARK8, Dardarin, ROCO 2, RIPK7, Leucine-rich repeat serine/threonine-protein kinase 2, augmented in rheumatoid arthritis 51
Mouse
R-Phycoerythrin (RPE)
Monoclonal
IgG1
Target Details
LRRK2 - View All LRRK2 Products
Human, Mouse, Rat
Recombinant Protein
Anti-LRRK2/Dardarin Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-500 of human LRRK2.
Anti-LRRK2/Dardarin Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests 83% similarity to mouse, 83% similarity to rat and no similarity to LRRK1.
Application Details
IHC, WB
Anti-LRRK2/Dardarin R-PE Conjugated Antibody is tested for Western Blots and Immunocytochemistry. Expect a band approximately >200 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
Formulation
1mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.1% (w/v) Sodium Azide
50% (v/v) Glycerol
Shipping & Handling
Wet Ice
Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
Expiration date is one (1) year from date of receipt.
LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Anti-LRRK2 is ideal for researchers interested in Neuroscience, specifically parkinsonism, as well as pathways related to the Electron Transport Chain and Wnt Signaling.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.