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Datasheet

KDEL Antibody

Rabbit Polyclonal

600-401-F85
200 µg
Liquid (sterile filtered)
WB, IHC, IF
Human, Mouse, Rat
Rabbit
$445.00 /Per Item
Out of stock
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Product Details

Anti-KDEL (RABBIT) Antibody - 600-401-F85
Lys Asp Glu Leu, K-D-E-L, ER lumen protein retaining receptor 1, KDEL endoplasmic reticulum protein retention, Kdelr1
Rabbit
Polyclonal
IgG

Target Details

KDELR1  - View All KDELR1 Products
Human, Mouse, Rat
Conjugated Peptide
KDEL Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against KDEL containing synthetic peptide immunogen.
Anti-KDEL Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with KDEL from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Recognizes KDEL proteins, GRP94, Grp78, PDI and calreticulin. It may also see ERp57 and ERp29. Cross-reactivity with KDEL from other sources has not been determined. Organell Marker research.
P24390 - UniProtKB
NP_006792.1 - NCBI Protein
10945 - Gene ID

Application Details

IF, IHC, WB
Anti-KDEL Antibody is tested for use in WB, IF, and IHC. Specific conditions for reactivity should be optimized by the end user.

Formulation

1 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
50% (v/v) Glycerol

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.