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IRF7 Antibody
Rabbit Polyclonal
600-401-H00
100 µg
Liquid (sterile filtered)
WB, ELISA, IHC, IF
Human, Mouse, Rat
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-IRF7 (RABBIT) Antibody - 600-401-H00
Interferon regulatory factor 7
Rabbit
Polyclonal
IgG
Target Details
IRF7 - View All IRF7 Products
Human, Mouse, Rat
Conjugated Peptide
IRF7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to the c-terminus of human IRF7.
Anti-IRF7 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with IRF7 with Human, Rat and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with IRF7 from other sources has not been determined.
Application Details
ELISA, IF, IHC, WB
Anti-IRF7 Antibody is tested for use in E, WB, IF, and IHC. Expect a band approximately ~54.2 kDa on specific lysates. Western Blot tested in human samples; Immunohistochemistry in human and mouse samples, and Immunofluorescence in mouse samples. Specific conditions for reactivity should be optimized by the end user.
Formulation
1 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.02% (w/v) Sodium Azide
None
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
IRF7 antibody detects the human IRF7. Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established. Anti-IRF7 antibodies are ideal for investigators involved in transcription factors, infectious disease and cytokines and growth factors research.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
