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Histone H2B pan Antibody
Rabbit Polyclonal IgG
600-401-X47
50 µg
Liquid (sterile filtered)
WB, ELISA, IF, ChIP
Human
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-Histone H2B pan (RABBIT) Antibody - 600-401-X47
Histone H2B type 1-C/E/F/G/I, Histone H2B.1A, Histone H2B.a, Histone H2B.g, Histone H2B.h, Histone H2B.k, Histone H2B.l
Rabbit
Polyclonal
IgG
Target Details
HIST1H2BC - View All HIST1H2BC Products
Human
Conjugated Peptide
Anti-Histone H2B pan Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing a sequence from the C-terminus of histone H4.
Anti-Histone H2B pan Antibody was purified by affinity purification. Cross reactivity with other species was not tested.
Application Details
ChIP, ELISA, IF, WB
Anti-Histone H2B pan Antibody has been tested by Chromatin Immunoprecipitation, western blot, Immunofluorescence, and ELISA. Specific conditions for reactivity should be optimized by the end user.
Formulation
1.46 mg/ml by UV absorbance at 280 nm
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
0.05% (w/v) Sodium Azide and 0.05% ProClin 300
None
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histones play a internal role in the regulation of transcription, DNA repair, DNA replication and chromosomal stability. These different functions are established via a complex set of post-translational modifications which either directly or indirectly alter chromatin structure and DNA accessibility to facilitate transcriptional activation or repression or other nuclear processes. Anti-Histone H2B pan Antibody is ideal for research in Chromatin Remodeling, Gene Expression and Epigenetics.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.