Datasheet is currently unavailable. Try again or CONTACT US
Datasheet

Desmin Antibody

Mouse Monoclonal DE-U-10 IgG1

200-301-P35
100 µg
Lyophilized
WB, IHC
Human, Mouse, Rat, Rabbit
Mouse
$485.00 /Per Item
Out of stock
Ships in approximately 14 days
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Product Details

Anti-Desmin (MOUSE) Antibody - 200-301-P35
CMD1I, CSM1, CSM2, intermediate filament protein
Mouse
Monoclonal
IgG1

Target Details

DES  - View All DES Products
Human, Mouse, Rat, Rabbit
Other
Desmin antibody was produced in mice by repeated immunizations with desmin from pig stomach.
Anti-Desmin antibody was purified from mouse ascites by protein A chromatography.  This product reacts with human, mouse, rat, and rabbit. Cross reactivity with Desmin from other sources has not been determined.
P02540 - UniProtKB
NP_001001535.1 - NCBI Protein
396725 - Gene ID

Application Details

IHC, WB
Anti-Desmin is tested for Immunohistochemistry -P and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~53.5 kDa corresponding to the appropriate cell lysate or extract.

Formulation

1.0 mg/mL by UV absorbance at 280 nm
1.2% sodium acetate
0.01% (w/v) Sodium Azide
2mg BSA
1.0 mL
Neutral PBS

Shipping & Handling

Ambient
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. DES gene encodes desmin, a muscle-specific cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball (1992) found that desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al. (1989) localized the gene to 2q35. Desmin mutation responsible for idiopathic dilated cardiomyopathy. This antibody is suitable for researchers interested in cancer research, cardiovascular diseases, neurodegenerative diseases, cell adhesion research, and cytoskeletal signaling research.

Invalid lot number

If you need help finding your CoA, contact us

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.