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Datasheet

CX3CR1 Antibody

Rabbit Polyclonal

600-401-G89
100 µg
Liquid (sterile filtered)
WB, ELISA, IHC, IF, FC
Human, Mouse, Rat
Rabbit
$475.00 /Per Item
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Product Details

Anti-CX3CR1 (RABBIT) Antibody - 600-401-G89
CMKBRL1, GPR13
Rabbit
Polyclonal
IgG

Target Details

CX3CR1  - View All CX3CR1 Products
Human, Mouse, Rat
Conjugated Peptide
CX3CR1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to an internal region of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids.
Anti-CX3CR1 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with CX3CR1 with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with CX3CR1 from other sources has not been determined.
P49238 - UniProtKB
NP_001164642.1 - NCBI Protein
1524 - Gene ID

Application Details

ELISA, FC, IF, IHC, WB
Anti-CX3CR1 Antibody is tested for use in E, WB, IHC, IF and FACS. Expect a band approximately ~40.3 kDa on specific lysates. Western Blot in human, mouse and rat samples; Immunohistochemistry in rat samples; Immunofluorescence in human, mouse and rat samples; Flow cytometry in human samples. Specific conditions for reactivity should be optimized by the end user.

Formulation

1 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.02% (w/v) Sodium Azide
None

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines. Anti-CX3CR1 is ideal for investigators involved in cytokines, growth factors and infectious disease research.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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