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Datasheet

CD8 APC Antibody

Mouse Monoclonal RPA-T8 IgG1 kappa

200-326-M64
500 µL
Liquid (sterile filtered)
FC
Human
Mouse
$275.00 /Per Item
Made to order
Ships in approximately 14 days
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Product Details

Anti-CD8 (MOUSE) Allophycocyanin Conjugated Monoclonal Antibody - 200-326-M64
T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL
Mouse
Allophycocyanine (APC)
Monoclonal
IgG1

Target Details

CD8A  - View All CD8A Products
Human
Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
Allophycocyanin conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8. Reactivity is observed against human CD8, chimpanzee, baboon, cynomolgus, rhesus, and ooty mangabey. Cross reactivity with CD8 from other sources has not been tested.
P01732 - UniProtKB
NP_001139345.1 - NCBI Protein
925 - Gene ID

Application Details

FC
Anti-CD8 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

Formulation

0.05 mg/mL Sufficient to run approximately 100 tests
0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.09% (w/v) Sodium Azide
0.1% Gelatin

Shipping & Handling

Wet Ice
Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
Expiration date is six (6) months from date of receipt.
CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.