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CD2AP phospho Y4-8-10 Antibody
Rabbit Polyclonal
1 References
600-401-J96
50 µg
Liquid (sterile filtered)
IHC
Human
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-CD2AP pY4-8-10 (RABBIT) Antibody - 600-401-J96
rabbit anti-CD2AP pY 4-8-10 Antibody, Adapter protein CMS, CD2AP, CD2-associated protein, Cas ligand with multiple SH3 domains, rabbit anti-CD2AP phosphorylated antibody
Rabbit
Polyclonal
IgG
Target Details
CD2AP - View All CD2AP Products
Human
Phosphorylation
Conjugated Peptide
Anti-CD2AP pY 4-8-10 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a phosphorylated synthetic peptide at Tyr-4-8-10 at the N-terminal of human CD2AP protein.
Anti-CD2AP pY4-8-10 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with CD2AP from other sources has not been determined.
Q9Y5K6 - UniProtKB
Application Details
IHC
- View References
Anti-CD2AP antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~71kDa corresponding to the appropriate cell lysate or extract.
Formulation
1.0mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
50% (v/v) Glycerol with 1 mg/ml Bovine Serum Albumin (BSA)
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
CD2-associated protein appears to act as an adapter protein between membrane proteins and the actin cytoskeleton. It may also be a factor in receptor clustering and cytoskeletal polarity between T-cell and antigen-presenting cell. It seems it could also anchor the podocyte slit diaphragm to the actin skeleton in renal glomerulus. It is required for cytokinesis. CD2AP is widely expressed in fetal and adult tissue, localized in the cytoplasm of cells. Anti-CD2AP pY4-8-10 Antibody is ideal for investigators interested in Signal Transduction research.
Balashova OA et al. (2024). Noncanonical function of folate through folate receptor 1 during neural tube formation. Nat Commun.
Applications
IHC, ICC, Histology
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.