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CAV1.2 Antibody
Mouse Monoclonal S57 IgG2b
200-301-F08
100 µg
Liquid (sterile filtered)
WB, IHC, IF, IP, Microarray
Human, Mouse, Rat
Mouse
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-CAV1.2 (MOUSE) Monoclonal Antibody - 200-301-F08
Voltage-dependent L-type calcium channel subunit alpha-1C, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, Smooth muscle calcium channel blocker receptor, CACB-receptor, Voltage-gated calcium channel subunit alpha Cav1.2
Mouse
Monoclonal
IgG2b
Target Details
CACNA1C - View All CACNA1C Products
Human, Mouse, Rat
Recombinant Protein
Cav1.2 Antibody was produced in mice by repeated immunizations with a fusion protein (intracellular carboxyl terminus) of rabbit Cav1.2.
Anti-CAV1.2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CAV1.2 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with CAV1.2 from other sources has not been determined. Channels and Transporters research.
P15381 - UniProtKB
NP_001129994.1 - NCBI Protein
Application Details
IF, IHC, IP, WB
Microarray
- View References
Anti-CAV1.2 Antibody has been tested in WB, IP, ICC/IF, and IHC and is suitable for use in microarray. Expect a band approximately ~240kDa (varies with cell background due to glycosylation) on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Formulation
1.0 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.09% (w/v) Sodium Azide
50% (v/v) Glycerol
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Specifically, Cav1.2 is a cardiac L-type calcium channel, and is important for excitation and contraction of the heart. It may be associated with a variant of Long QT syndrome called Timothy's syndrome and also with Brugada syndrome. Some references also suggest it is related to bipolar disease as well.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.