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Catenin gamma (Plakoglobin) Antibody
Mouse Monoclonal 15F11 IgG1
200-301-P27
100 µg
Lyophilized
WB, IHC
Human, Bovine
Mouse
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-Catenin gamma (Plakoglobin) (MOUSE) Antibody - 200-301-P27
DP3, PDGB, PKGB, CTNNG, DPIII, ARVD12, Catenin gamma, Desmoplakin III, Desmoplakin-3
Mouse
Monoclonal
IgG1
Target Details
JUP - View All JUP Products
Human, Bovine
Recombinant Protein
Catenin gamma (Plakoglobin) antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to chicken plakoglobin.
Anti-Catenin gamma (Plakoglobin) antibody was purified from mouse ascites by protein A chromatography. This product reacts with human and bovine. Cross reactivity with Catenin gamma from other sources has not been determined.
Application Details
IHC, WB
Anti-Catenin gamma is tested for Immunohistochemistry -F, immunocytochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~81.8 kDa corresponding to the appropriate cell lysate or extract.
Formulation
100µg/mL by UV absorbance at 280 nm
1.2% sodium acetate
0.01% (w/v) Sodium Azide
2mg BSA
1.0 mL
Neutral PBS
Shipping & Handling
Ambient
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Junction Plakoglobin (JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. This antibody is suitable for researchers interested in cell adhesion and cancer research.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.