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Beta Amyloid pyro E11 Antibody
Rabbit Polyclonal
600-401-J13
50 µg
Liquid (sterile filtered)
WB
Human, Primate
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-Beta Amyloid pyro E11 (RABBIT) Antibody - 600-401-J13
rabbit anti-Beta Amyloid pyro E11 Antibody, ß-amyloid pyro E11, Alzheimer disease amyloid protein, Beta amyloid, A-beta, ABPP, APPI
Rabbit
Polyclonal
IgG
Target Details
APP - View All APP Products
Human, Primate
Pyroglutamate
Conjugated Peptide
beta Amyloid [Pyro Glu11] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N-terminus 11-pyro E start point of human beta Amyloid.
Anti-Beta Amyloid pyro Glu11 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific to the N-terminus 11-pyro E start point. A BLAST analysis was used to suggest cross-reactivity with Human and Primate based on 100% sequence homology. Cross-reactivity with beta Amyloid pyro Glu11 from other sources has not been determined.
Application Details
WB
Anti-Beta Amyloid pyro Glu11 antibody has been tested by western blot and is useful for ELISA, Western Blot and Immunostaining. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~86.9kDa corresponding to the appropriate cell lysate or extract.
Formulation
0.75mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
None
30% Glycerol
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is six (6) months from date of receipt.
The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. Beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. Beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. Beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. Beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease. Anti-beta Amyloid [Pyro Glu11] antibody is ideal for researchers interested Alzheimer's Research, Cell Cycle and Replication, and Neuroscience research.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
