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AP2M1 Antibody
Chicken Polyclonal
600-901-G75
100 µg
Liquid (sterile filtered)
WB, ELISA, IHC, IF
Human, Mouse, Rat
Chicken
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-AP2M1 (Chicken) Antibody - 600-901-G75
CLAPM1, KIAA0109
Chicken
Polyclonal
IgY
Target Details
AP2M1 - View All AP2M1 Products
Human, Mouse, Rat
Conjugated Peptide
AP2M1 Antibody was produced in chicken by repeated immunizations with a peptide near the c-terminus of human AP2M1.
Anti-AP2M1 Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with AP2M1 with Human, Rat and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with AP2M1 from other sources has not been determined.
Application Details
ELISA, IF, IHC, WB
Anti-AP2M1 Antibody is tested for use in E, WB, IF, and IHC. Western Blot tested in human samples; Immunohistochemistry and Immunofluorescence tested in mouse samples. All other applications and species not yet tested. Expect a band approximately ~49.6kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Formulation
1.0 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
AP2M1 antibody detects human AP2M1. The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist. Anti-AP2M1 antibodies are ideal for investigators involved in infectious disease and enzyme research.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.