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Aha1 Antibody
Rabbit Polyclonal
1 References
100-401-E82
100 µL
Liquid (sterile filtered)
WB, IHC
Human, Mouse, Rat
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-Aha1 (RABBIT) Antibody - 100-401-E82
Aha1, SHSA1, HspC322, p38, Activator of 90 kDa heat shock protein ATPase homolog 1
Rabbit
Polyclonal
Antiserum
Target Details
Ahsa1 - View All Ahsa1 Products
Human, Mouse, Rat
Recombinant Protein
Aha1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with Mouse Aha1.
Anti-Aha 1 Antibody was purified by Protein A chromatography. A BLAST analysis was used to suggest cross-reactivity with Aha 1 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Aha1 from other sources has not been determined. Heat Shock research.
Q8BK64 - UniProtKB
NP_666148.1 - NCBI Protein
Application Details
IHC, WB
Anti-Aha1 Antibody has been tested in western blot, ICC, and IHC and is suitable for use in ELISA, IF microscopy and IP. Expect a band approximately ~38kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Formulation
85 mg/mL by Refractometry
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding. It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors.
Jinwal U et al. (2013). Reconstructing the Hsp90/Tau Machine. Current Enzyme Inhibition
Applications
WB, IB, PCA
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
