Rat RAGE ELISA Kit
KOA0599
1 Kit
ELISA
Rat
78 pg/ml - 5000 pg/ml
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Rat RAGE AccuSignal ELISA Kit - KOA0599
Advanced glycosylation end product specific receptor, Advanced glycosylation end product-specific receptor, Ager, DAMA 358M23.4, LE 9211 A antigen, MAPK MAK MRK overlapping kinase, MGC22357, MOK, OTTHUMP00000174885, RAGE 1, RAGE isoform NtRAGE-delta, RAGE isoform sRAGE-delta, RAGE_HUMAN, RAGE1, Receptor for advanced glycation end products, receptor for advanced glycation end-products variant 20, Receptor for advanced glycosylation end products, Renal tumor antigen, Renal tumor antigen, Renal tumor antigen 1
ELISA Kit
78 pg/ml - 5000 pg/ml
Target Details
AGER - View All AGER Products
Rat
Expression system for standard: NSO; Immunogen sequence: Q24-A342
Natural and recombinant rat RAGE. There is no detectable cross-reactivity with other relevant proteins.
Application Details
ELISA
Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1ml per well of the 5000pg/ml, 2500pg/ml, 1250pg/ml, 625pg/ml, 312pg/ml, 156pg/ml, 78pg/ml rat RAGE standard solutions into the precoated 96-well plate. Add 0.1ml of the sample diluent buffer into the control well (Zero well). Add 0.1ml of each properly diluted sample of rat cell culture supernatants, serum or plasma(heparin, EDTA) to each empty well. We recommend that each rat RAGE standard solution and each sample is measured in duplicate.
Formulation
Heparin Sodium
1 kit
Shipping & Handling
Wet Ice
Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
See kit insert for complete instructions.
RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as “AGER”. AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B(NF-kappaB).
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