Human MBP-C - MBL2 ELISA Kit
KOA0476
1 Kit
ELISA
Human
312 pg/ml - 20000 pg/ml
Shipping info:
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Product Details
Human MBP-C/MBL2 AccuSignal ELISA Kit - KOA0476
COLEC1, Collectin-1, Lectin mannose-binding soluble 2, Mannan binding lectin, Mannan binding protein, Mannose binding lectin 2 soluble, Mannose binding lectin 2 soluble, Mannose binding lectin, Mannose binding lectin protein C2 soluble opsonic defect, Mannose binding protein, Mannose binding protein C, Mannose binding protein C precursor, Mannose-binding lectin, MBL, MBL2_HUMAN, MBL2D, MBP 1, MBP, MBP1, MBPB, MBPC, MBPD, Opsonic defect, protein C, Soluble mannose binding lectin
ELISA Kit
312 pg/ml - 20000 pg/ml
Target Details
MBL2 - View All MBL2 Products
Human
Expression system for standard: NSO; Immunogen sequence: E21-I248
Natural and recombinant human MBP-C. There is no detectable cross-reactivity with other relevant proteins.
P11226 - UniProtKB
NP_000233.1 - NCBI Protein
Application Details
ELISA
Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1ml per well of the 20000pg/ml, 10000pg/ml, 5000pg/ml, 2500pg/ml, 1250pg/ml, 625pg/ml, 312pg/ml human MBP-C standard solutions into the precoated 96-well plate. Add 0.1ml of the sample diluent buffer into the control well (Zero well). Add 0.1ml of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human MBP-C standard solution and each sample be measured in duplicate.
Formulation
Heparin Sodium
Shipping & Handling
Wet Ice
Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
See kit insert for complete instructions.
MBL2, also called mannose-binding lectin (protein C) 2, soluble or Mannose-binding lectin (MBL) is a lectin that is instrumental in innate immunity. MBL2 is mapped to chromosome 10q11.2-q21. It belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL2 recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding MBL2 to a micro-organism results in activation of the lectin pathway of the complement system. Another important function of MBL2 is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.
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