Human GDF15 ELISA Kit
KOA0453
1 Kit
ELISA
Human
31.2 pg/ml - 2000 pg/ml
Shipping info:
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Product Details
Human GDF-15 AccuSignal ELISA Kit - KOA0453
Growth/differentiation factor 15, Macrophage inhibitory cytokine 1, MIC 1, NAG-1, NRG-1, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, PDF, PLAB, Placental bone morphogenetic protein, Placental TGF-beta, Prostate differentiation factor, PROSTATE-DERIVED FACTOR, PTGFB
ELISA Kit
31.2 pg/ml - 2000 pg/ml
Target Details
GDF15 - View All GDF15 Products
Human
Expression system for standard: CHO; Immunogen sequence: A197-I308
Natural and recombinant human GDF-15. There is no detectable cross-reactivity with other relevant proteins.
Q99988 - UniProtKB
NP_004855.2 - NCBI Protein
Application Details
ELISA
Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1ml per well of the 2000pg/ml,1000pg/ml, 500pg/ml, 250pg/ml, 125pg/ml, 62.5pg/ml, 31.2pg/ml human GDF-15 standard solutions into the precoated 96-well plate. Add 0.1ml of the sample diluent buffer into the control well (Zero well). Add 0.1ml of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human GDF-15 standard solution and each sample be measured in duplicate.
Formulation
Heparin Sodium
1 Kit
Shipping & Handling
Wet Ice
Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
See kit insert for complete instructions.
GDF-15(Growth differentiation factor 15),also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB, is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. Using FISH, the MIC1 gene is mapped to 19p13.2-p13.1. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF15 showed increased expression and secretion during erythroblast maturation. GDF15 functions as an anti-inflammatory cytokine by directly interfering with chemokine signaling and integrin activation.
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