Human CXCL10 - IP-10 ELISA Kit
KOA0429
1 Kit
ELISA
Human
31.2 pg/ml - 2000 pg/ml
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Human CXCL10/IP-10 AccuSignal ELISA Kit - KOA0429
10 kDa interferon gamma-induced protein, C7, Chemokine CXC motif ligand 10, Crg 2, CRG2, CXCL10, CXL10_HUMAN, Gamma IP10, gIP 10, GIP10, IFI10, INP 10, Interferon activated gene 10, Interferon gamma induced cell line, Interferon inducible cytokine IP10, IP 10, IP-10, MOB1, SCYB10, Small inducible cytokine B10, Small inducible cytokine B10 precursor, Small inducible cytokine subfamily B (Cys X Cys) member 10, Small inducible cytokine subfamily B CXC member 10, Small-inducible cytokine B10
ELISA Kit
31.2 pg/ml - 2000 pg/ml
Target Details
CXCL10 - View All CXCL10 Products
Human
Expression system for standard: E.coli; Immunogen sequence: V22-P98
Natural and recombinant human CXCL10. There is no detectable cross-reactivity with other relevant proteins.
P02778 - UniProtKB
NP_001556.2 - NCBI Protein
Application Details
ELISA
Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1ml per well of the 2000pg/ml,1000pg/ml, 500pg/ml, 250pg/ml, 125pg/ml, 62.5pg/ml, 31.2pg/ml human CXCL10 standard solutions into the precoated 96-well plate. Add 0.1ml of the sample diluent buffer into the control well (Zero well). Add 0.1ml of each properly diluted sample of human cell culture supernates, serum, plasma( heparin, EDTA), saliva or urine to each empty well. It is recommended that each human CXCL10 standard solution and each sample be measured in duplicate.
Formulation
Heparin Sodium
1 Kit
Shipping & Handling
Wet Ice
Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
See kit insert for complete instructions.
Chemokine(C-X-C motif) ligand 10(CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein(gamma-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. It is a potent inhibitor of angiogenesis in vivo. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. It is a RAS target gene and is overexpressed in the majority of colorectal cancers. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.
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